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Crtac1tm1Kota
Targeted Allele Detail
Summary
Symbol: Crtac1tm1Kota
Name: cartilage acidic protein 1; targeted mutation 1, Kohtaro Takei
MGI ID: MGI:5141316
Gene: Crtac1  Location: Chr19:42271474-42421405 bp, - strand  Genetic Position: Chr19, 36.07 cM
Alliance: Crtac1tm1Kota page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:174418
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation details: Exon 1 was replaced with a floxed neo cassette via homologous recombination. Immunohistochemical analysis confirmed the absence of protein expression in E14 brains from homozygous mice. (J:174418)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 2 assay results
In Structures Affected by this Mutation: 1 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Crtac1 Mutation:  45 strains or lines available
References
Original:  J:174418 Sato Y, et al., Cartilage acidic protein-1B (LOTUS), an endogenous Nogo receptor antagonist for axon tract formation. Science. 2011 Aug 5;333(6043):769-73
All:  9 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory